Dermatoscopy: A Non-Invasive Skin Lesion Diagnostic Technique And Its Applications

What Is Dermatoscopy?

Dermatoscopy, is a noninvasive method that enables clinicians to evaluate fully - using a magnified oil immersion diascopy - numerous morphological features, not visible with the naked eye, which enhances the diagnosis of nearly all pigmented skin lesions.This examination can help doctors identify and differentiate skin lesions, such as moles, rashes, infections, and skin cancers. Its features include magnification capability, non-invasiveness, real-time imaging, image recording, and polarized light technology.

What Types of Dermatoscopy Are There?

Dermatoscopy is a non-invasive skin diagnostic technique that involves magnifying and illuminating the skin's surface to observe microscopic structures. The types include Handheld dermatoscopes - the most basic type, where doctors can directly observe skin lesions using a handheld device. polarized-light dermatoscopes use polarized light technology to reduce reflections from the skin's surface, making deeper structures more visible. Immersion dermatoscopes use oil or water mediums between the lens and skin to improve image clarity and resolution. Digital dermatoscopes incorporate digital imaging technology, allowing for capturing, storing, and analyzing high-resolution images, facilitating record-keeping and comparison of lesion changes. Reflectance confocal microscopes are an advanced dermatoscope technology that provides near-histological clarity with high-resolution images, enabling the observation of deeper skin structures. portable dermatoscopes are designed to be lightweight and convenient for use in different settings. Workstation dermatoscopes are typically connected to computer workstations and equipped with advanced image analysis and processing software. Dermatoscope imaging systems integrate diagnostic systems, photography techniques, and report printing, providing clear imaging and convenient operation.

Dermatoscopic Features of Pigmented Lesions

The dermatoscopic features of pigmented lesions can provide important diagnostic clues for doctors. Here are some common dermatoscopic features of pigmented lesions:

Pigment network is the most common Dermatoscopy presentation in melanocytic lesions. The network structure typically appears as brown streaks on a diffuse light brown background, covering most of a specific lesion. Globular structures are pigmented round or oval brown or grayish-black clumps of varying sizes, seen in Clark nevi and papillomatous intradermal nevi (Unna nevi). Ovoid blue-gray nests can be seen in pigmented basal cell carcinomas, appearing as well-defined, loosely connected oval nests or elongated areas, usually bluish-gray. Blue-gray globules are round or oval bluish-gray structures, which may appear brown or pinkish depending on the location of pigment within the tumor nests, often found in the dermal papillae or reticular dermis. Arborizing vessels are bright red vessels longer than 1mm, with a main trunk diameter ≥0.2mm and irregular branching patterns, typically representing the tumor's neovascular system.

Other features include radial streaming, which is radiating projections surrounding a central darker area (axis), with the projections appearing brown, blue, or gray, and the center appearing dark brown, blue, or black. The blue-white veil is a diffuse, confluent bluish-gray to bluish-white structure coexisting with different pigment networks, dots/globules, or streaks, almost exclusively seen in melanomas and Spitz/Reed nevi. pigment deposition refers to diffusely distributed deep brown to grayish-black areas, excluding structures with more refined features like pigment networks or vascular structures. Irregular pigment streaking, visible as irregular pigment extensions in malignant melanoma, is an important diagnostic clue. The blue-white veil exists in some pigmented BCCs, but its mere presence is not a key indicator for distinguishing pigmented BCCs from invasive melanomas in Chinese populations. These features are crucial for differentiating benign and malignant pigmented lesions, but the final diagnosis still requires considering clinical presentations, patient history, and histopathological examination when necessary.

Dermatoscopy Technique

Dermatoscopy is a non-invasive skin diagnostic method that involves magnifying and observing the skin's surface and subsurface structures using specific instruments, enabling more accurate identification and diagnosis of skin lesions. Dermatoscopy plays a vital role in the daily work of dermatologists, improving diagnostic accuracy and facilitating early detection of skin lesions. Here are some key points about the dermatoscopy technique:

  • Definition: A dermatoscope (also known as a chemiluminescence microscope, incident light microscope, or skin surface microscope) is a non-invasive technique that allows observation of subsurface structures in the epidermis, dermal-epidermal junction, and papillary dermis.
  • Classification: Dermatoscopes can be classified based on the imaging principle into immersion and polarized light types, or based on whether the lens contacts the skin into contact and non-contact types. There are also portable and workstation dermatoscopes, with the latter often connected to computers and pre-installed with various software applications.
  • Applications: Dermatoscopes are primarily used to examine pigmented and non-pigmented skin lesions, helping doctors determine whether a skin biopsy, referral to a specialist, or continuous monitoring is needed.
  • Process: The dermatoscopy process includes cleaning the skin, using the dermatoscope to observe or photograph the lesion area, and the doctor making a diagnosis based on the observed images.
  • Advantages: As a non-invasive tool, dermatoscopy can significantly improve diagnostic accuracy for pigmented and non-pigmented lesions, reducing the need for blind surgical excisions or biopsies.
  • Image quality control: To ensure the accuracy of dermatoscopy, image quality control is necessary, including appropriate lighting, resolution, and contrast.
  • Diagnostic Terminology: Dermatoscopy diagnostic terminology includes metaphoric (analogical) terms and descriptive terms, with standardized terms aiding communication between doctors and diagnostic accuracy.
  • Vascular signs: Vascular signs observed under the dermatoscope provide valuable auxiliary information for diagnosing inflammatory or tumor-related skin conditions.

Effectiveness of Dermoscopy Examination

Non-invasive: Dermoscopy is a non-invasive technique, which means it does not cause any trauma or discomfort to the skin. As an auxiliary diagnostic tool, dermoscopy can significantly improve the diagnostic accuracy of pigmented and non-pigmented skin lesions. Moreover, dermoscopy examinations are quick and can provide immediate diagnostic results. Dermoscopy can also observe skin structures and changes that are not visible to the naked eye, such as those in the epidermis, dermal-epidermal junction, and upper dermis. The clinical application of dermoscopy reduces the probability of trauma caused by blind surgical excision or biopsy, avoiding unnecessary surgical excision. Dermoscopy examination can effectively guide the scope of surgical excision, postoperative follow-up, and the selection of appropriate physical therapy methods. Dermoscopy can not only dynamically monitor the disease course of skin lesions and suspicious lesions in high-risk populations but also, due to the high-definition imaging systems of modern dermoscopy equipment, facilitate detailed observation by doctors. Many dermoscopy devices are designed to be portable and easy to operate, with some even capable of connecting to smart devices for the convenience of doctors and patients. For pediatric patients, dermoscopy examination reduces the painful detection means of invasive examinations.

Dermatoscopy steps: preparation stage - the patient needs to clean the skin in the examination area. Examination process - the doctor carefully observes the suspected lesion area using the dermatoscope. Image recording - if necessary, the doctor will take pictures of the lesion area for analysis and recordkeeping. Diagnosis and recommendations - based on the observations, the doctor will provide a preliminary diagnosis and suggest further examinations or treatments.

Precautions for Dermoscopy Examination

Before undergoing a dermoscopy examination, patients should ensure that the skin in the area to be examined is clean and dry. Before the examination, cosmetics should be avoided on the lesion site, and no cosmetics or colored products should be applied, as this may affect the examination results. Since dermoscopy is non-traumatic, patients generally do not require special preoperative preparation. The examination is performed with the assistance of a dermoscope, and the doctor will provide necessary guidance to the patient before the operation. Additionally, skin disinfection or other procedures are usually completed by the doctor or nursing staff, and the patient does not need to handle them independently. During the examination, patients need not feel fear or anxiety about the process; they should simply maintain a relaxed state. After the examination, the doctor may provide further diagnostic or treatment recommendations based on the observed images. Patients who require regular monitoring of skin lesions should follow medical advice and undergo regular follow-up examinations.

People May Ask

Does A Malignant Mole Hurt?

Furthermore, malignant moles may cause no pain at all. However, in the event of a pigmented mole, this signifies melanoma. Certain moles that develop into cancer can also cause discomfort or peculiar sensitivity that is distinct from the surrounding skin.

Dermatologists Treat Which Types of Cancer?

Dermatologists, or medical professionals that specialize in treating skin conditions, treat the majority of basal and squamous cell malignancies as well as pre-cancers.

What Is Dermatology That Is Precancerous?

Skin cell alterations that increase the likelihood of cancer development are known as precancerous abnormalities of the skin. Currently, actinic keratosis is not cancer. However, it could progress to squamous cell carcinoma, a kind of non-melanoma skin cancer, if left untreated. Solar keratosis is another name for actinic keratosis.

What Are The Signs That A Mark Is Melanoma?

The lesion or mole has been altering in size, shape, color, or appearance; it's also expanding into a previously normal-looking patch of skin. Additionally, melanoma may cause a mole or lesion's texture to change, becoming lumpy or hard.

What Are The Telltale Symptoms That A Skin Spot Is A Malignant Melanoma?

Often, a mole that changes in size, shape, or color is the first indication of melanoma. There are two warning indicators of melanoma in this case: color fluctuations and an uneven border. Anywhere on your body, melanomas can form.

A Benign Tumor, What Size Is It?

As 80% of lung nodules with a diameter of less than 2 cm are benign, the more benign a tumor appears on a radiograph, the smaller it appears. Though they are not the only indicators of benign tumors, smoothed radiopaque density with distinct edges characterize the majority of benign nodules.

How Big Does A Benign Tumor Typically Get?

When benign soft tissue tumors are located superficially, they rarely grow larger than two centimeters on average. However, deep tumors can grow up to several inches before being discovered, such as peripheral nerve tumors and angiomyolipoma.

Are Cancerous Tumors Soft Or Hard?

Tumors may feel hard on the exterior, but studies have revealed that the individual cells within the tissue are not all the same rigidity; in fact, the tumors can vary in softness throughout.

How Is The Malignant Status of A Spot Determined?

What skin cancer appears likeChanging your mole or getting a mole that appears unique.Instead,dome-shaped development.Scaly patch.Instead,a sore that doesn't heal or one that heals then returns.Instead,beneath a nail, a brown or black streak.

What Makes A Dermatoscope Different from A Dermoscope?

A noninvasive in vivo method called dermoscopy is mainly employed to examine skin lesions [1]. Skin-surface microscopy, incident light microscopy, dermatoscopy, and epiluminescence microscopy are synonyms. A handheld device known as a dermatoscope is used to perform dermoscopy.

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How Can Dermoscopy Images Be Captured?

Dermoscopy images can be captured and stored in different ways, such as: • Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.• Using a digital camera

Dermoscopy images can be captured and stored in different ways, such as:

• Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.
• Using a digital camera with dermoscopic adapter, there’s 49mm screw size camera adapter available to order now.

Compatible phone/tablet models:
All iPhone models, 95% Android phones, 90% tablet. For phone/tablet size in 5.25-14mm

Compatible camera models:
All camera with built 49mm filter screw, such as Canon EOS 70D, 80D, 90D; Canon EOS R7, R10, R50, R100; Canon M100, M200, M50, Mark II; Canon G7X Mark III, Sony ZV-1

How Can I Connect My Phone to My Dermatoscope?

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide. Smartphone Connector (1) Place phone adapter screw in the center of smartphone’s

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide.

Smartphone Connector

(1) Place phone adapter screw in the center of smartphone’s main camera.
(2) Screw magnet attachment on phone adapter.
(3) Put dermoscope’s back ring and magnet attachment together

Take The Best Images

You need to adjust the focus ring after the dermoscpe connected on smartphone to get the best images.

How Can I Clean My Dermoscopy after Usage?

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always follow the manufacturer’s instructions. However, some general steps are:

• Turn off and disconnect your dermoscopy from any power source or device.

• Wipe off any visible dirt or debris from the dermoscopy with a soft cloth or tissue.

• Disinfect the dermoscopy with an alcohol-based wipe or spray, or a disinfectant solution recommended by the manufacturer. Make sure to cover all surfaces, especially the lens and contact plate.

• Let the dermoscopy air dry completely before storing it in a clean and dry place.

• Do not use abrasive or corrosive cleaners, solvents, or detergents that may damage the dermoscopy.

• Do not immerse the dermoscopy in water or any liquid, unless it is waterproof and designed for immersion.

You should clean your dermoscopy after each use, or at least once a day if you use it frequently. You should also check your dermoscopy regularly for any signs of damage or malfunction, and contact the manufacturer or service provider if needed.

Polarized VS Non-Polarized Dermoscopy

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can improve the diagnose accuracy of skin lesions, such as melanoma,basal cell carcinoma, seborrheic keratosis, etc.

There are two main types of dermoscopy: Non polarized and polarized dermoscopy.We’ve fitted most of our dermoscopys with polarized and non-polarized light. They canbe used in multiple skin structures.

Non-polarized contact Mode

In non-polarized mode, the instrument can provide information about the superficialskin structures, such as milia-like cysts, comedo-like openings, and pigment in theepidemis.

The dermoscopy requires applying a liquid such as mineral oil or alcohol to the skin andplacing the lens in contact with the skin. This reduces surface reflection and enhancesthe view of subsurface structures.

Image with non-polarized light (DE-3100)

Polarized contact Mode

In polarized mode, the instrument allows for visualization for deeper skin structures,such as blood vessels, collagen, and pigment in the dermis.

The dermoscopy does not need to be in contact with the skin or use any liquid. Theirpolarized light can help to eliminate surface reflection and allow visualization ofvascular structures.

Image with polarized light (DE-3100)

Polarized non-contact Mode

The dermoscopy can also use polarized light to examine the skin without direct contact.

In polarized non-contact mode, the instrument allows for examination infected areasand lesions that are painful for the patient, or the difficult to contact pigmented lesions,such as nails and narrow areas.

The contact plate should be removed in this mode, and it does not require applying aliquid to the skin. As it doesn’t require pressure or fluid application on the skin, it canalso avoid cross-contamination and infection risk.

Image in polarized non-contact mode (DE-3100)

How Effectiveness Is Dermoscopy

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination. The dermoscopy allows the

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination.

The dermoscopy allows the examination of skin lesions with magnification and illumination. This can be greatly avoiding the factors that cause interference to visual detection. Such as lighting, skin color, hair and cosmetics.

Several studies have demonstrated that dermoscopy is useful in the identification of melanoma, when used by a trained professional.

It may improve the accuracy of clinical diagnosis by up to 35%
It may reduce the number of harmless lesions that are removed
In primary care, it may increase the referral of more worrisome lesions and reduce the referral of more trivial ones

A 2018 Cochrane meta-analysis published the accuracy of dermoscopy in the detection.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 76 75 3.04 0.32
Dermoscopy with visual inspection (in person) 92 95 18 0.08
Image-based visual inspection alone (not in person) 47 42 0.81 1.3
Dermoscopy with image-based visual inspection (not in person) 81 82 4.5 0.23
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

As we can see, the dermoscope can improve the accuracy of diagnosis of skin lesions, especially melanoma.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 79 77 3.4 0.27
Dermoscopy with visual inspection (in person) 93 99 93 0.07
Image-based visual inspection alone (not in person) 85 87 6.5 0.17
Dermoscopy with image-based visual inspection (not in person) 93 96 23 0.07
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

Characteristics of the dermatoscopic structure of the skin lesions include:

• Symmetry or asymmetry
• Homogeny/uniformity (sameness) or heterogeny (structural differences across the lesion)
• Distribution of pigment: brown lines, dots, clods and structureless areas
• Skin surface keratin: small white cysts, crypts, fissures
• Vascular morphology and pattern: regular or irregular
• Border of the lesion: fading, sharply cut off or radial streaks
• Presence of ulceration

There are specific dermoscopic patterns that aid in the diagnosis of the following pigmented skin lesions:

• Melanoma
• Moles (benign melanocytic naevus)
• Freckles (lentigos)
• Atypical naevi
• Blue naevi
• Seborrhoeic keratosis
• Pigmented basal cell carcinoma
• Haemangioma

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