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Keratin proliferation in the skin is referred to as Keratosis. This excessive accumulation of keratin can manifest in skin abnormalities resembling patches, verrucae, or nevi. For instance, Actinic keratoses frequently present as smaller areas of skin with a rough texture, whereas seborrheic keratoses may mimic the appearance of a wart or nevus. 14th January 2023
The color spectrum varies significantly, encompassing hues from a pale tan to a deep black. Initially, it may draw attention due to its soft and velvety texture, appearing both visually and tactilely smooth, and sometimes in miniature sizes. However, as time progresses, seborrheic keratoses undergo a transformation, becoming scaly and acquiring a thickness reminiscent of melted candle wax adhering to the skin's surface.
Ointments formulated with bioactive vitamin D3 are commonly employed in the management of inflammatory skin conditions characterized by keratinization, including psoriasis. Additionally, senile warts or seborrheic keratoses, which are non-malignant growths, predominantly affect individuals in advanced age groups.
The likelihood of seborrheic keratoses arising from HPV or any other viral entity is remote, and they do not pose a contagious threat.
Considerations in Diagnostic Evaluation
When assessing the differential diagnosis of seborrheic keratoses clinically, it encompasses a range of possibilities such as malignant melanoma, melanocytic nevi, common warts (verruca vulgaris), acuminate condyloma, fibroepithelial polyps, epidermal nevi, actinic keratoses, as well as pigmented basal and squamous cell carcinomas. Updated on Oct 14, 2020.
A seborrheic keratosis develops progressively, exhibiting specific indications and manifestations. These may comprise a rounded or oval protrusion with a waxy or coarse texture, commonly observed on facial regions, the chest, a shoulder, or the back. Additionally, it can manifest as a flat or slightly elevated bump, characterized by a scaly surface and a distinctive "stuck-on" appearance.
In a clinical setting, seborrheic keratoses exhibit a matte, wax-like, and verrucous texture, which gives them their distinct "adherent" visual aspect. The hue of these skin lesions ranges from light to dark brown, yellow, and gray, and they can manifest as a solitary lesion or in clusters of tens or even hundreds (see Images.May 6, 2024).
Despite the clinical morphological similarities between SK and epidermal nevus, the distinct geometric characteristics of the lesions can aid in their differentiation. SKs are typically round to oval in shape, whereas epidermal nevi exhibit a more elongated, linear pattern and are frequently of a larger size.