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Dermoscopy of Alopecia Areata

Alopecia areata is a type of hair disease showed hair loss or baldness. It happens when immune system mistakenly attacks hair follicles, causing hair loss. Some hair fall out and then regrow and may fall out again. While some alopecia areata will never regrow hair back. It varies in kinds of complicated situation. Dermoscopy is…

Alopecia areata is a type of hair disease showed hair loss or baldness. It happens when immune system mistakenly attacks hair follicles, causing hair loss. Some hair fall out and then regrow and may fall out again. While some alopecia areata will never regrow hair back. It varies in kinds of complicated situation. Dermoscopy is a special significant instrument to detect and diagnose alopecia areara.

What is alopecia areata?
Alopecia areata is one of the common types of hair loss. Alopecia areata most typically appearance on the scalp or beard, showing a round or oval bald patch, without hair. And alopecia areata also can happen on anywhere of the body. Alopecia areata is an autoimmune disease which caused by attack from immune system to hair follicles that form hair in skin.

What causes alopecia areate?
When immune system mistakenly attacks hair follicles, leading in alopecia areata. There are not clear reports about what exactly causes the immune attack on hair follicles, but some key factors include:
Genetic Factors: There are genetic factors in the development of alopecia areata due to it has a family tendency.
Autoimmune Factors:The immune system mistakenly targets hair follicles, resulting in hair loss.
Environmental Factors: An exotic virus or another substance happened in the body or other environmental changes may contribute to the development of alopecia areata.

alopecia areata
alopecia areata

Clinical features of alopecia areate
Alopecia areata usually presents as localized patchy hair loss, ranging from small round patches on the scalp to total body hair loss. It may also affect hair in other parts of the body. The typical clinical features of alopecia areata as following:
Patchy hair loss: Patchy hair loss is the most common form of presentation, with round or oval patches of hair loss and normal skin growth around the patches.
Distribution: Alopecia areata most often occurs on the scalp, but it may also occur in the beard, eyebrows, eyelashes and limbs. Complete follicular openings: The complete follicular openings are directly visible under the dermatoscope.
Positive pull test: Pulling hair will cause hair loss
Terminal hair: In bald patches, terminal hair is completely lost. Others: itching, burning or tingling, no active folliculitis and no symptoms such as erythema, desquamation or pustules around the hair follicles.

Dermatoscopic features of alopecia areata
Dermoscopy is a non-invasive aiding medical instrument that allows precise and tiny details of structures or patterns which are invisible by naked eyes. Dermoscopy of hair, also known as trichoscopy, is ideal and reliable device because it can eliminate light reflection and glare from the surface of the skin. Sometimes it is difficult to distinguish scarring alopecia from non-scarring alopecia, in which case dermoscopy can be really helpful. There are some key dermoscopic features like below:
Yellow spots: Yellow spots can be seen in both acute and chronic alopecia areata and they are yellow circular structures, usually located around the opening of the hair follicle. The presence of yellow spots may be related to inflammation and immune responses.
Black spots: Black spots is a common dermoscopic feature that indicates alopecia areata is in active state . Black spots present broken hairs at the opening of the hair follicle, usually black or brown. They may appear in the center or edges of hair loss patches.
Conical hair: This is a specific dermoscopic feature that shows tiny conical, short and spiky hair tapers gradually toward the scalp, similar to an exclamation point.
Broken hair: Broken hair are short, fractured and broken hairs usually appears in the affected area or the edges of hair loss patches.
Hypopigmentation villi: Hypopigmentation villi are hair that is sparse, short and light in color. This feature usually appears in remission of alopecia areata.

dermatoscopic features of alopecia areata
dermatoscopic features of alopecia areata

Uses of dermoscope in alopecia areata
Dermoscopy palys a crucial roles in the detection and diagnosis of alopecia areata. There are some typical uses:
1, According to dermatoscopic features of alopecia areata, dermoscopy can accurately distinguish alopecia areata from other types of hair loss, such as scarring alopecias, involutional alopecia, alopecia universalis, trichotillomania, and so on.
2, By dermoscope, skin doctors can exclude other possible causes, like fungal infection, etc.
3, Under the dermoscopy, it is clearly to evaluate the activity and severity of alopecia areata, then to make suitable treatment project

Dermoscopy for the treatment and follow up of alopecia areata
Evaluate the treatment effect: Dermoscopy can give feedback to the treatment effect of alopecia areata, So that skin doctor can analyse and evaluate if the treatment project need to be adjust or not.
Monitor relapse and detect new lesion: Dermoscopy, as a monitor, can inspect the whole process of alopecia areata, including its regrowth, relapse or new lesion.
Cooperate with treatment: By using of dermoscopy and combining with internal and external medication or other treatment methods, it greatly increase the cure effect of alopecia areata.

trichoscopy dermatoscope DE-4100
trichoscopy dermatoscope DE-4100

Notes of the use of dermoscopy in self-examination
It is no doubt that dermoscopy is very useful and reliable device in the diagnosis of alopecia areata. While, there are some notes when people use dermoscopy for self-examination.
Firstly, it is important to rightly operate a dermoscopy and carefully observe the alopecia areata in the process of the examination.
Secondly, skin doctors can compare and analyse the changes of images under dermoscopy, or images photoed by dermoscopy.
Thirdly, when a suspicious finding happened, it is necessary to ask a professional dermatologist for help.

Alopecia areata is a autoimmune skin disease. Even in some cases, hair can regrow back. But it takes undefined time. It may take 6 weeks or 1 year or more long time for hair regrowing. When hair regrow, and it may fall out again. Such situations happen time and again. And some alopecia areata represents, and it will not regrow any more. The development of alopecia areata is very complicated, so it is very important to use dermoscopy to detect and monitor alopecia areata.

No matter patients or skin doctors, all of them should know how to use dermoscopy in right ways. Especially, patients who have alopecia areata diagnosed. Pay more attention to alopecia areata and keep self-examination by dermoscopy. Any suspicious findings, keep in touch with professional skin doctors and cooperate with doctors in diagnosis and treatment.

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How can dermoscopy images be captured?

Dermoscopy images can be captured and stored in different ways, such as: • Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.• Using a digital camera

Dermoscopy images can be captured and stored in different ways, such as:

• Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.
• Using a digital camera with dermoscopic adapter, there’s 49mm screw size camera adapter available to order now.

Compatible phone/tablet models:
All iPhone models, 95% Android phones, 90% tablet. For phone/tablet size in 5.25-14mm

Compatible camera models:
All camera with built 49mm filter screw, such as Canon EOS 70D, 80D, 90D; Canon EOS R7, R10, R50, R100; Canon M100, M200, M50, Mark II; Canon G7X Mark III, Sony ZV-1

How can I connect my phone to my dermatoscope?

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide. Smartphone Connector (1) Place phone adapter screw in the center of smartphone’s

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide.

Smartphone Connector

(1) Place phone adapter screw in the center of smartphone’s main camera.
(2) Screw magnet attachment on phone adapter.
(3) Put dermoscope’s back ring and magnet attachment together

Take The Best Images

You need to adjust the focus ring after the dermoscpe connected on smartphone to get the best images.

How can I clean my dermoscopy after usage?

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always follow the manufacturer’s instructions. However, some general steps are:

• Turn off and disconnect your dermoscopy from any power source or device.

• Wipe off any visible dirt or debris from the dermoscopy with a soft cloth or tissue.

• Disinfect the dermoscopy with an alcohol-based wipe or spray, or a disinfectant solution recommended by the manufacturer. Make sure to cover all surfaces, especially the lens and contact plate.

• Let the dermoscopy air dry completely before storing it in a clean and dry place.

• Do not use abrasive or corrosive cleaners, solvents, or detergents that may damage the dermoscopy.

• Do not immerse the dermoscopy in water or any liquid, unless it is waterproof and designed for immersion.

You should clean your dermoscopy after each use, or at least once a day if you use it frequently. You should also check your dermoscopy regularly for any signs of damage or malfunction, and contact the manufacturer or service provider if needed.

Polarized VS Non-polarized Dermoscopy

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can improve the diagnose accuracy of skin lesions, such as melanoma,basal cell carcinoma, seborrheic keratosis, etc.

There are two main types of dermoscopy: Non polarized and polarized dermoscopy.We’ve fitted most of our dermoscopys with polarized and non-polarized light. They canbe used in multiple skin structures.

Non-polarized contact Mode

In non-polarized mode, the instrument can provide information about the superficialskin structures, such as milia-like cysts, comedo-like openings, and pigment in theepidemis.

The dermoscopy requires applying a liquid such as mineral oil or alcohol to the skin andplacing the lens in contact with the skin. This reduces surface reflection and enhancesthe view of subsurface structures.

Image with non-polarized light (DE-3100)

Polarized contact Mode

In polarized mode, the instrument allows for visualization for deeper skin structures,such as blood vessels, collagen, and pigment in the dermis.

The dermoscopy does not need to be in contact with the skin or use any liquid. Theirpolarized light can help to eliminate surface reflection and allow visualization ofvascular structures.

Image with polarized light (DE-3100)

Polarized non-contact Mode

The dermoscopy can also use polarized light to examine the skin without direct contact.

In polarized non-contact mode, the instrument allows for examination infected areasand lesions that are painful for the patient, or the difficult to contact pigmented lesions,such as nails and narrow areas.

The contact plate should be removed in this mode, and it does not require applying aliquid to the skin. As it doesn’t require pressure or fluid application on the skin, it canalso avoid cross-contamination and infection risk.

Image in polarized non-contact mode (DE-3100)

How effectiveness is dermoscopy

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination. The dermoscopy allows the

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination.

The dermoscopy allows the examination of skin lesions with magnification and illumination. This can be greatly avoiding the factors that cause interference to visual detection. Such as lighting, skin color, hair and cosmetics.

Several studies have demonstrated that dermoscopy is useful in the identification of melanoma, when used by a trained professional.

It may improve the accuracy of clinical diagnosis by up to 35%
It may reduce the number of harmless lesions that are removed
In primary care, it may increase the referral of more worrisome lesions and reduce the referral of more trivial ones

A 2018 Cochrane meta-analysis published the accuracy of dermoscopy in the detection.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 76 75 3.04 0.32
Dermoscopy with visual inspection (in person) 92 95 18 0.08
Image-based visual inspection alone (not in person) 47 42 0.81 1.3
Dermoscopy with image-based visual inspection (not in person) 81 82 4.5 0.23
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

As we can see, the dermoscope can improve the accuracy of diagnosis of skin lesions, especially melanoma.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 79 77 3.4 0.27
Dermoscopy with visual inspection (in person) 93 99 93 0.07
Image-based visual inspection alone (not in person) 85 87 6.5 0.17
Dermoscopy with image-based visual inspection (not in person) 93 96 23 0.07
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

Characteristics of the dermatoscopic structure of the skin lesions include:

• Symmetry or asymmetry
• Homogeny/uniformity (sameness) or heterogeny (structural differences across the lesion)
• Distribution of pigment: brown lines, dots, clods and structureless areas
• Skin surface keratin: small white cysts, crypts, fissures
• Vascular morphology and pattern: regular or irregular
• Border of the lesion: fading, sharply cut off or radial streaks
• Presence of ulceration

There are specific dermoscopic patterns that aid in the diagnosis of the following pigmented skin lesions:

• Melanoma
• Moles (benign melanocytic naevus)
• Freckles (lentigos)
• Atypical naevi
• Blue naevi
• Seborrhoeic keratosis
• Pigmented basal cell carcinoma
• Haemangioma

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