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Dermoscopy of Bowen Disease

Bowen disease, also known as squamous cell carcinoma in situ, is a squamous cell carcinoma that occurs within the epidermis of the skin and mucous membranes. Bowen’s disease, although relatively benign in clinical presentation, is histologically characterized as carcinomatous in nature. If left untreated, the tumor cells in some cases eventually move down into the…


Enhance Bowen Disease Dermoscopy Detection with - IBOOLO

IBOOLO's advanced dermoscopy tools are revolutionising the early detection of Bowen disease. High-resolution imaging and precision diagnostics help clinicians identify critical features like irregular vessels and scales, improving diagnostic accuracy and patient outcomes.

Dermoscopy in Bowen Disease: A Practitioner's Guide to Early Detection

Bowen disease, or squamous cell carcinoma in situ, is a non-invasive skin cancer that poses a significant diagnostic challenge. Its subtle appearance, often resembling common skin conditions, makes accurate identification with the naked eye difficult. However, dermoscopy in Bowen disease has emerged as an indispensable tool, revealing microscopic clues that facilitate early and precise diagnosis. This article is designed for clinicians and students, offering a practical guide to the dermoscopic features of Bowen disease, best practices for examination, and strategies for confident differentiation from other skin lesions.

The Unique Dermoscopic Features of Bowen Disease

Unlike many other skin conditions, Bowen disease lacks a single, definitive dermoscopic feature. Instead, it is characterized by a combination of key signs, with vascular patterns being the most crucial. Recognizing these features is the cornerstone of effective Bowen disease dermoscopy.

Key Diagnostic Signs

When examining a suspected lesion, a combination of these features is highly indicative of Bowen disease:

  • Irregular Vascular Patterns: This is the most consistent and important clue. Look for dotted, comma-shaped, or linear vessels. Their distribution is often chaotic, lacking the symmetrical arrangement seen in benign lesions.
  • White or Yellowish Scales: The surface of the lesion is frequently covered with scales, which can be diffuse or patchy. These scales reflect the abnormal keratinization characteristic of the condition.
  • Glomerular or "Coiled" Vessels: These small, tightly-coiled vessels are a hallmark feature of Bowen disease. They can appear individually or in clusters.
  • Pigmentation: While not always present, some Bowen disease lesions show irregular brown or black pigmentation with blurred, asymmetrical borders. This can make them easily confused with melanoma.
  • Erosions or Ulceration: In more advanced cases, superficial erosions or crusting may be present.

By using an advanced dermatoscope, such as those from IBOOLO, clinicians can clearly visualize these subtle features, significantly improving diagnostic confidence.

How to Differentiate Bowen Disease from its Mimics

A major challenge in dermatology is differentiating Bowen disease from other common skin conditions. Dermoscopy provides the critical details needed for this task. Here is a comparative guide to aid in your differential diagnosis.

Bowen Disease vs. Psoriasis

While both conditions feature scales and a reddish background, their vascular patterns are distinct. Psoriasis typically shows a regular distribution of dotted vessels over an erythematous base, often described as the "red dot sign." In contrast, Bowen disease dermoscopy reveals irregularly arranged dotted and coiled vessels.

Bowen Disease vs. Basal Cell Carcinoma (BCC)

BCC often presents with classic features like arborizing vessels (tree-like) and blue-gray ovoid nests. Bowen disease, however, lacks these features and instead shows the hallmark irregular dotted and coiled vessels. The surface of BCC may also have a pearly, translucent quality that is not seen in Bowen disease.

Bowen Disease vs. Seborrheic Keratosis

Seborrheic keratosis is characterized by comedo-like openings, milia-like cysts, and a "stuck-on" appearance. These features are absent in Bowen disease, which is defined by its specific vascular and scale patterns. While both can be pigmented, seborrheic keratosis typically has a well-organized, "cerebriform" (brain-like) surface pattern.

The Clinical Protocol for Dermoscopic Examination

A standardized approach ensures diagnostic accuracy and efficiency. The following protocol integrates Bowen disease dermoscopy into a seamless workflow.

1. Patient History and Visual Assessment

  • Document the patient's sun exposure history and any changes in the lesion.
  • Visually inspect the lesion to note its size, color, and location.

2. Scalp and Skin Preparation

  • Clean the lesion area to remove any scales, oils, or creams that might obstruct the view.
  • For some dermoscopes, applying a contact medium like gel or alcohol can enhance image clarity.

3. Dermoscopic Examination

  • Place the dermoscope on or near the lesion, adjusting the light source and magnification. Use polarized light to reduce glare and visualize vessels more effectively.
  • Systematically scan the entire lesion and its borders, focusing on the key diagnostic signs mentioned above.

4. Documentation and Follow-Up

  • Capture and archive high-resolution images. This is essential for long-term monitoring and for documenting treatment efficacy.
  • Based on the dermoscopic findings, recommend either a biopsy for histopathological confirmation or an appropriate treatment plan.

The IBOOLO Advantage in Dermoscopy for Bowen Disease

The quality of your dermatoscope directly impacts your ability to make an accurate diagnosis. **IBOOLO** dermatoscopes are designed with cutting-edge technology to enhance Bowen disease dermoscopy.

  • Superior Optics: Our high-magnification, multi-coated lenses provide crystal-clear images, ensuring you don't miss any of the subtle vascular or structural features.
  • Optimal Lighting: With both polarized and non-polarized lighting modes, you can switch seamlessly to observe both surface scales and deep, irregular vessels.
  • Seamless Integration: Our devices offer easy digital connectivity, allowing for high-quality image capture for patient records and remote consultation.

By choosing an IBOOLO dermatoscope, you gain a powerful tool that combines precision, convenience, and reliability, making the diagnosis of Bowen disease more confident and efficient.

The Future of Bowen Disease Management

Dermoscopy has transformed the management of Bowen disease. By providing a non-invasive, real-time view of critical microscopic features, it has significantly improved diagnostic accuracy and reduced the need for unnecessary biopsies. From early detection to guiding treatment decisions, dermoscopy in Bowen disease is an indispensable tool in modern dermatology. For clinicians, mastering this technique is vital. For patients, regular skin checks with a dermatologist using a high-quality dermatoscope are the best way to ensure skin health and catch any suspicious lesions in their earliest, most treatable stage.

Bowen disease, also known as squamous cell carcinoma in situ, is a squamous cell carcinoma that occurs within the epidermis of the skin and mucous membranes. Bowen’s disease, although relatively benign in clinical presentation, is histologically characterized as carcinomatous in nature. If left untreated, the tumor cells in some cases eventually move down into the dermis and develop into classic squamous cell carcinoma.

Dermoscopy is a non-invasive, quick and easy test. Through dermoscopy, the doctor can observe the skin structures of Bowen’s disease, such as pigmentation, blood vessel distribution, and other features that can provide a basis for diagnosis.

Overview of Bowen Disease

Bowen’s disease is a squamous carcinoma in situ of the skin that occurs only in the cells of the stratum corneum of the skin without breaking through the basement membrane bands of the skin. It is most common in middle-aged and older adults and can occur on the skin and mucous membranes anywhere on the body, most often on the head, face, and extremities. Long-term sunlight exposure to ultraviolet radiation can damage intracellular DNA, and when DNA repair is delayed or fails, normal epithelial cells may become cancerous. The course of the disease is slow, with light or dark red papules and small patches in the early stage, which may gradually increase in size and merge into plaques of different sizes and irregular shapes, with a flat surface, and hyperkeratosis and crusting are common.

Several years after the onset of Bowen’s disease, malignant tumors of the integumentary system may develop. Therefore, Bowen’s disease should be followed up periodically after detection to observe the development of malignant tumors in the visceral system.

Bowen Disease
Bowen Disease

Dermoscopy Techniques

The optical system of a dermatoscope usually consists of multiple sets of magnifying lenses that magnify the image of the skin surface several times, making it easy to observe the structure and color changes of the skin. The dermoscopy process is relatively simple and short. However, it should be noted that the skin surface to be examined needs to be carefully cleaned before the examination, and the observation should be adjusted to the appropriate focal length.

Dermoscopy can magnify the details of the skin of patients with Bowen’s disease and help doctors observe the characteristic manifestations of Bowen’s disease-like papulopapular disorder, such as the size, shape, and color of the macular rash, as well as the covering of greasy scabs and scales. This helps doctors to better treat their patients.

What does Bowen Skin Cancer Look Like?

Bowen skin cancer lesions are initially red spots, round or oval, gradually expanding and irregular in shape. The surface is often accompanied by keratinized scales, and the boundary of the lesion is clear, which may be slightly elevated, and there are generally no self-conscious symptoms. Chronic eczema and Bowen’s disease have some similarity in the morphology of the lesions, manifested as erythema of the skin, accompanied by itching, easy to recur. However, chronic eczema usually has obvious itching symptoms and a longer course.

Bowen Skin Cancer

Specific Dermoscopic Features of Pigmented Bowen’s Disease

The dermoscopy of Bowen disease is often characterized by clustered distributions of punctate, coiled blood vessels. This vascular structure is highly specific in Bowen’s disease and is one of the most important clues to the diagnosis of the disease. The surface of the lesions in Bowen’s disease is usually accompanied by scales, which are caused by hyperkeratosis of the epidermis. Pigmented Bowen’s disease is relatively rare, and its dermatoscopic features, in addition to the typical manifestations described above, are characterized by the following specific features: brown keratotic structureless area, homogenous area of different shades and brown-to-blue-gray dots/ peppering. 

Differential Diagnosis of Bowen Disease

Bowen disease usually presents as an intraepidermal abnormality, whereas superficial basal cell carcinoma often occurs on the trunk, especially the back and chest. Whereas malignant melanoma is a pigmented tumor, Bowen’s disease does not necessarily contain pigment.Pigmented Bowen’s disease is rare. It is commonly described in dark skin individuals and on the sun-protected areas.

Dermoscopy not only magnifies the lesions, but also clearly shows the pigmentation and blood vessels of the skin. Different skin diseases will present different skin patterns, and dermoscopy can be very helpful in differentiating between them.

Clinical Case Studies

Clinically, Bowen’s disease usually presents as well-defined, irregularly shaped light-red or dark-red papules or plaques with a few scales or crusts on the surface, with no obvious characteristic manifestations, which can be easily confused with other diseases.

Clinical Images of Bowen's Disease
Clinical Images of Bowen’s Disease

The vascular structure of Bowen’s disease is usually characterized by dots, clumps or lines in dermoscopy, and glomerular blood vessels are also one of the classic features. And structureless pigmentation is often seen in dermoscopy.

Dermoscopy of Bowen Disease
Dermoscopy of Bowen Disease

Dermoscopy is capable of observing fine structures that cannot be seen by the naked eye, such as glomerulonephric blood vessels and structureless pigmentation, etc. These features are of great significance in the diagnosis of Bowen’s disease. Bowen’s disease is easily confused with psoriasis, eczema and solar keratosis. Dermoscopy can show the specific dermoscopic features of different diseases, which can help doctors to make differential diagnosis.

Treatment and Management of Bowen Disease

Surgical removal of the Bowen’s disease tissue completely is one of the common treatments for larger skin lesions. Bowen’s disease can also be cured by rapid freezing of the damaged area by a medical professional using liquid nitrogen, which causes necrosis of the diseased tissue through extremely low temperatures. Photodynamic therapy is another commonly used treatment, which is usually well tolerated, has mild side effects, and is cosmetically effective.

Once cured, patients with Bowen’s disease should avoid sun exposure and eat a light diet while maintaining a good state of mind. And doctors consider following up each case of Bowen’s disease depending on the size of the lesions, treatment modality and immunosuppression.

Prevention and Screening for Bowen Disease

When outdoors, try to avoid prolonged exposure to sunlight during periods of intense UV light. Regular skin examinations can help detect Bowen’s disease early. Through examination by a medical professional, abnormal changes in the skin, such as dark red, brownish-red or brown patches, can be detected in time for further diagnosis and treatment.

In the early detection of Bowen’s disease, dermoscopy, as a non-invasive, quick and easy method of diagnosing skin disorders, can quickly help doctors to determine how far the lesions have progressed.


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How can dermoscopy images be captured?

Dermoscopy images can be captured and stored in different ways, such as: • Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.• Using a digital camera

Dermoscopy images can be captured and stored in different ways, such as:

• Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.
• Using a digital camera with dermoscopic adapter, there’s 49mm screw size camera adapter available to order now.

Compatible phone/tablet models:
All iPhone models, 95% Android phones, 90% tablet. For phone/tablet size in 5.25-14mm

Compatible camera models:
All camera with built 49mm filter screw, such as Canon EOS 70D, 80D, 90D; Canon EOS R7, R10, R50, R100; Canon M100, M200, M50, Mark II; Canon G7X Mark III, Sony ZV-1

How can I connect my phone to my dermatoscope?

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide. Smartphone Connector (1) Place phone adapter screw in the center of smartphone’s

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide.

Smartphone Connector

(1) Place phone adapter screw in the center of smartphone’s main camera.
(2) Screw magnet attachment on phone adapter.
(3) Put dermoscope’s back ring and magnet attachment together

Take The Best Images

You need to adjust the focus ring after the dermoscpe connected on smartphone to get the best images.

How can I clean my dermoscopy after usage?

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always follow the manufacturer’s instructions. However, some general steps are:

• Turn off and disconnect your dermoscopy from any power source or device.

• Wipe off any visible dirt or debris from the dermoscopy with a soft cloth or tissue.

• Disinfect the dermoscopy with an alcohol-based wipe or spray, or a disinfectant solution recommended by the manufacturer. Make sure to cover all surfaces, especially the lens and contact plate.

• Let the dermoscopy air dry completely before storing it in a clean and dry place.

• Do not use abrasive or corrosive cleaners, solvents, or detergents that may damage the dermoscopy.

• Do not immerse the dermoscopy in water or any liquid, unless it is waterproof and designed for immersion.

You should clean your dermoscopy after each use, or at least once a day if you use it frequently. You should also check your dermoscopy regularly for any signs of damage or malfunction, and contact the manufacturer or service provider if needed.

Polarized VS Non-polarized Dermoscopy

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can improve the diagnose accuracy of skin lesions, such as melanoma,basal cell carcinoma, seborrheic keratosis, etc.

There are two main types of dermoscopy: Non polarized and polarized dermoscopy.We’ve fitted most of our dermoscopys with polarized and non-polarized light. They canbe used in multiple skin structures.

Non-polarized contact Mode

In non-polarized mode, the instrument can provide information about the superficialskin structures, such as milia-like cysts, comedo-like openings, and pigment in theepidemis.

The dermoscopy requires applying a liquid such as mineral oil or alcohol to the skin andplacing the lens in contact with the skin. This reduces surface reflection and enhancesthe view of subsurface structures.

Image with non-polarized light (DE-3100)

Polarized contact Mode

In polarized mode, the instrument allows for visualization for deeper skin structures,such as blood vessels, collagen, and pigment in the dermis.

The dermoscopy does not need to be in contact with the skin or use any liquid. Theirpolarized light can help to eliminate surface reflection and allow visualization ofvascular structures.

Image with polarized light (DE-3100)

Polarized non-contact Mode

The dermoscopy can also use polarized light to examine the skin without direct contact.

In polarized non-contact mode, the instrument allows for examination infected areasand lesions that are painful for the patient, or the difficult to contact pigmented lesions,such as nails and narrow areas.

The contact plate should be removed in this mode, and it does not require applying aliquid to the skin. As it doesn’t require pressure or fluid application on the skin, it canalso avoid cross-contamination and infection risk.

Image in polarized non-contact mode (DE-3100)

How effectiveness is dermoscopy

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination. The dermoscopy allows the

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination.

The dermoscopy allows the examination of skin lesions with magnification and illumination. This can be greatly avoiding the factors that cause interference to visual detection. Such as lighting, skin color, hair and cosmetics.

Several studies have demonstrated that dermoscopy is useful in the identification of melanoma, when used by a trained professional.

It may improve the accuracy of clinical diagnosis by up to 35%
It may reduce the number of harmless lesions that are removed
In primary care, it may increase the referral of more worrisome lesions and reduce the referral of more trivial ones

A 2018 Cochrane meta-analysis published the accuracy of dermoscopy in the detection.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 76 75 3.04 0.32
Dermoscopy with visual inspection (in person) 92 95 18 0.08
Image-based visual inspection alone (not in person) 47 42 0.81 1.3
Dermoscopy with image-based visual inspection (not in person) 81 82 4.5 0.23
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

As we can see, the dermoscope can improve the accuracy of diagnosis of skin lesions, especially melanoma.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 79 77 3.4 0.27
Dermoscopy with visual inspection (in person) 93 99 93 0.07
Image-based visual inspection alone (not in person) 85 87 6.5 0.17
Dermoscopy with image-based visual inspection (not in person) 93 96 23 0.07
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

Characteristics of the dermatoscopic structure of the skin lesions include:

• Symmetry or asymmetry
• Homogeny/uniformity (sameness) or heterogeny (structural differences across the lesion)
• Distribution of pigment: brown lines, dots, clods and structureless areas
• Skin surface keratin: small white cysts, crypts, fissures
• Vascular morphology and pattern: regular or irregular
• Border of the lesion: fading, sharply cut off or radial streaks
• Presence of ulceration

There are specific dermoscopic patterns that aid in the diagnosis of the following pigmented skin lesions:

• Melanoma
• Moles (benign melanocytic naevus)
• Freckles (lentigos)
• Atypical naevi
• Blue naevi
• Seborrhoeic keratosis
• Pigmented basal cell carcinoma
• Haemangioma

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