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Dermoscopy of Sebaceous Hyperplasia

Sebaceous hyperplasia is commonly found on the forehead and cheeks, where lesions are localised in scattered, raised, rounded papules. Although sebaceous hyperplasia itself does not usually pose a serious health risk, it may affect the appearance to some extent, especially if the pimples appear in conspicuous places such as the face, causing psychological burden. Dermoscopy…

Sebaceous hyperplasia is commonly found on the forehead and cheeks, where lesions are localised in scattered, raised, rounded papules. Although sebaceous hyperplasia itself does not usually pose a serious health risk, it may affect the appearance to some extent, especially if the pimples appear in conspicuous places such as the face, causing psychological burden. Dermoscopy is a non-invasive test that clearly shows the features of sebaceous hyperplasia lesions, such as a yellowish background and yellowish lobulated structures. These features provide an important basis for the diagnosis of sebaceous hyperplasia.


Overview of Sebaceous Hyperplasia
Sebaceous hyperplasia is a benign lesion resulting from the enlargement of normal sebaceous glands within the skin. It is most common in people between the ages of 20 and 30, as well as in the elderly. The exact cause and pathogenesis of sebaceous hyperplasia is not fully understood. Aging of the skin, genetic factors, and endocrine disorders may all contribute to sebaceous hyperplasia. Sebaceous hyperplasia usually presents cosmetically as single or multiple, variably sized papules on the skin. These papules tend to be similar in colour to skin colour or slightly yellowish, and have a softer texture.
Skin aging is an important factor in sebaceous hypoplasia. As we age, the natural physiological processes of the skin lead to sebaceous hypoplasia, which in turn may trigger sebaceous hypoplasia. When the sebaceous glands produce too much sebum, it may lead to blockage of the follicular opening, which in turn leads to inflammation. Although sebaceous hypoplasia itself does not directly cause rosacea, both are associated with abnormal activity of the sebaceous glands.

Sebaceous Hyperplasia
Sebaceous Hyperplasia


Dermoscopy Techniques
Dermoscopy magnifies the surface of the skin through the use of an optical magnification system so that the physician can see the texture and details of the skin surface more clearly. As a result, dermoscopy can clearly show the yellow papules of sebaceous hypoplasia and the surrounding ring of blood vessels.
Before the dermoscopy begins, the area of skin to be examined needs to be thoroughly cleaned. If the IBOOLO DE-3100 is used, then next hold the lens of the DE-3100 close to the skin surface of the area to be observed and adjust the magnification and focusing distance of the dermatoscope to ensure that the details of the skin can be clearly seen during observation.


Dermoscopic Features of Sebaceous Hyperplasia
On dermoscopy, sebaceous hypoplasia usually appears as a well-defined yellow to creamy-white cloudy structure with clear borders. Telangiectasia is common but tends to be uniform.sebaceous hypoplasia usually occurs in the vicinity of hair follicles and, together with the follicles, constitutes the follicular sebaceous glandular system. Sebaceous hyperplasia can be single or multiple, and is prevalent on the forehead and cheeks, usually in a scattered distribution.


Sebaceous Hyperplasia
Basal cell carcinoma usually presents as small, pearly nodules, pink or brown in colour, with a smooth surface, sometimes accompanied by tiny vasodilatations. Sebaceous hyperplasia, on the other hand, presents mainly as an increase in the size of the sebaceous glands, with the formation of pimples, acne, greasy scales, and skin roughness. It usually appears as small nodules on the skin, ranging from a few millimetres to several centimetres in diameter, and tend to be round or oval in shape.
Dermoscopy is able to visualise structures and features of the lower epidermis, papillary dermis and deeper dermis that are not visible to the naked eye, and which have a specific and relatively clear correspondence with histopathological changes in the skin.

Dermoscopy of Sebaceous Hyperplasia
Dermoscopy of Sebaceous Hyperplasia


Dermoscopy in Therapeutic Decision-making
Sebaceous hyperplasia usually appears dermoscopically as a yellow to creamy-white cystic structure, sometimes accompanied by a central umbilical depression or opening. These features help the physician to make a definitive diagnosis of sebaceous hyperplasia so that other similar skin lesions can be ruled out. Based on dermoscopic observations, the doctor can determine the severity of sebaceous hypoplasia, the extent of the lesion and whether it is accompanied by other skin problems. For mild sebaceous hypoplasia, the doctor may recommend conservative treatments such as medication and lifestyle modifications. For moderately severe sebaceous hyperplasia or with other skin problems, doctors may recommend more aggressive treatment options such as laser therapy and surgery.


Clinical Case Study of Sebaceous Hyperplasia
Case Description:
The patient, an elderly male, presented with scattered, hemispherical, raised, yellowish papules on the forehead and cheeks. The papules were approximately 2-3 mm in diameter, soft, and commonly had an umbilical depression in the centre.
Dermoscopic images:
On dermoscopy, sebaceous hypoplasia appears as a yellowish-white nodular pattern. The openings of the glands are seen in small pits or umbilical depressions in the centre of such nodules.
Image interpretation:
The yellowish-white nodular pattern suggests hyperplasia of the sebaceous glands. The pits or umbilical recesses in the centre of the nodules are openings for sebaceous gland ducts.

Sebaceous Hyperplasia Dermoscopy
Sebaceous Hyperplasia Dermoscopy


Exploring Treatment Options for Sebaceous Hyperplasia
There are three main common treatment options for sebaceous hypoplasia, laser therapy, electrodesiccation and topical medication. Laser treatment involves direct application of specific wavelengths of laser light to sebaceous gland tissues. It is suitable for superficial and small amount of sebaceous hypoplasia. Electrodrying method is to use high-frequency power supply with higher voltage and lower current intensity to burn and destroy the lesion tissue. It is suitable for larger and deeper sebaceous hypoplasia. Commonly used drugs for topical medication include retinoids, antibiotics (e.g., fusidic acid cream), and anti-sebaceous hormones.
After treatment, patients should have regular rechecks so that doctors can understand the changes in the condition and adjust the treatment plan in time. If there are abnormalities, such as worsening of symptoms, relapse, etc., you should seek medical advice in time.


Strategies to Prevent Sebaceous Hyperplasia
Strategies to prevent sebaceous hypoplasia can be categorised into two main types, proper skin care and maintaining a healthy lifestyle. Skin care refers to the use of gentle cleansing products that can be used to clean the skin in daily life to avoid clogging of pores. Healthy lifestyle refers to maintaining a balanced diet, adequate sleeping time, a good state of mind, and proper physical exercise.
Daily care is essential for people with sebaceous hyperplasia who have been treated or are undergoing treatment. Skin care can help maintain clean and hygienic skin and reduce the occurrence of clogged pores and inflammation. In addition, proper diet and routine can regulate the endocrine system, thereby reducing the risk of sebaceous hypoplasia.

Sebaceous Hyperplasia Dermoscopy: Skin Lesion Insights - IBOOLO

Sebaceous Hyperplasia Dermoscopy by IBOOLO reveals precise skin imaging. Non-invasive techniques detect subtle changes, offering accurate diagnosis of this common condition.

Sebaceous Hyperplasia Dermoscopy: A Comprehensive Diagnostic and Management Guide

Distinguishing from Similar Conditions

Accurately differentiating sebaceous hyperplasia from other skin lesions is crucial for appropriate management. The complexity of sebaceous hyperplasia dermoscopy lies in the subtle yet significant morphological and dermoscopic variations:

Basal Cell Carcinoma (BCC)

Visual Distinctions: BCC: Pearly, translucent appearance with irregular borders. Sebaceous Hyperplasia: Uniform, yellow-white, well-defined structures revealing characteristic sebaceous hyperplasia dermoscopy features.

Dermoscopic Indicators: BCC: Arborizing blood vessels, blue-gray ovoid nests. Sebaceous Hyperplasia: Consistent vascular pattern, central umbilication distinctive in sebaceous hyperplasia dermoscopy analysis.

Skin Tags (Acrochordons)

Structural Differences: Skin Tags: Pedunculated, soft, skin-colored growths. Sebaceous Hyperplasia: Sessile, slightly raised, yellow-white papules with unique dermoscopic characteristics.

Key Diagnostic Markers: Skin Tags: Irregular surface, variable size. Sebaceous Hyperplasia: Uniform size, consistent color pattern evident in detailed sebaceous hyperplasia dermoscopy examination.

Comparative Characteristics

Milia: Tiny, white, keratin-filled cysts. Sebaceous Hyperplasia: Larger, yellow-tinted, glandular structures with distinctive dermoscopic features.

Dermoscopic Evaluation and 

Milia: Bright white, crystalline appearance. Sebaceous Hyperplasia: Soft, translucent yellow background typical of sebaceous hyperplasia dermoscopy findings.

Treatment Approaches: Personalized Intervention Strategies

Conservative Management

Conservative treatments represent the first-line approach for managing sebaceous hyperplasia, focusing on minimal intervention and symptom management:

Topical Treatments

1. Retinoid-Based Therapies

- Mechanism: Regulate sebaceous gland activity

- Examples: Tretinoin, adapalene

- Benefits: Reduce glandular hyperplasia, Improve skin texture and Minimal side effects.

2. Chemical Exfoliants

Active Ingredients: Salicylic acid, Glycolic acid and Lactic acid.

Therapeutic Goals: Normalize skin cell turnover, Reduce sebum production and Improve overall skin appearance.

Treatment Selection Criteria

Determining the most appropriate intervention requires a comprehensive assessment:

Comprehensive Evaluation Parameters

1. Clinical Considerations:

Lesion size and quantity, Location on the body, Patient's aesthetic concerns and Potential psychological impact.

2. Patient-Specific Factors

Age and skin typeMedical history, Previous treatment responses and Potential contraindications.

3. Risk-Benefit Analysis

Invasiveness of procedure, Potential scarring, Recovery time and Long-term efficacy.

Lifestyle and Preventive Strategies

Comprehensive Lifestyle Recommendations

1. Nutritional Interventions

Anti-inflammatory diet, Omega-3 fatty acid supplementation, Reduced sugar intake and Increased hydration.

2. Stress Management

Mindfulness practices, Regular exercise, Adequate sleep and Stress reduction techniques.

3. Environmental Protection

Daily broad-spectrum sunscreen, Protective clothing, Avoiding excessive sun exposure and Pollution mitigation strategies.

Proactive Skin Management

A holistic approach to skin health extends beyond individual treatments:

Integrated Skin Care Approach

1. Professional Monitoring

Regular dermatological check-ups, Advanced imaging technologies and Comprehensive skin assessments.

2. Personalized Skincare Regimens

Tailored cleansing routines, Specialized moisturization and Targeted treatment protocols.

3. Early Intervention Strategies

Continuous skin evaluation, Prompt addressing of changes and Preventive maintenance.

Patient Communication: Empowerment Through Understanding

1. Educational Approach

  • Demystifying the condition
  • Explaining medical terminology
  • Providing comprehensive information

2. Emotional Support

  • Addressing cosmetic concerns
  • Managing psychological impacts
  • Building patient confidence

3. Treatment Expectation Management

  • Realistic outcome discussions
  • Potential treatment limitations
  • Long-term management strategies
 

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Who Can perform Dermoscopy?

The powerful magnification and lighting capabilities dermatoscopes offer provide beneficial visual data for everyone to understand the current state of their skin and track changes over time. However, specialized medical training is typically required to analyze dermoscopy images and determine if biopsies or treatment are necessary. Dermatologists have this expertise.

amelanotic melanoma dermoscopy – IBOOLO

IBOOLO is a camera lens manufacturer based in China with more than 11+ years of experience in manufacturing, catering to a variety of requirements. We have become experts in the design and manufacture of a wide variety of Dermatoscope, Microscope, Macro lens and Woods Lamp.

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How can dermoscopy images be captured?

Dermoscopy images can be captured and stored in different ways, such as: • Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.• Using a digital camera

Dermoscopy images can be captured and stored in different ways, such as:

• Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.
• Using a digital camera with dermoscopic adapter, there’s 49mm screw size camera adapter available to order now.

Compatible phone/tablet models:
All iPhone models, 95% Android phones, 90% tablet. For phone/tablet size in 5.25-14mm

Compatible camera models:
All camera with built 49mm filter screw, such as Canon EOS 70D, 80D, 90D; Canon EOS R7, R10, R50, R100; Canon M100, M200, M50, Mark II; Canon G7X Mark III, Sony ZV-1

How can I connect my phone to my dermatoscope?

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide. Smartphone Connector (1) Place phone adapter screw in the center of smartphone’s

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide.

Smartphone Connector

(1) Place phone adapter screw in the center of smartphone’s main camera.
(2) Screw magnet attachment on phone adapter.
(3) Put dermoscope’s back ring and magnet attachment together

Take The Best Images

You need to adjust the focus ring after the dermoscpe connected on smartphone to get the best images.

How can I clean my dermoscopy after usage?

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always follow the manufacturer’s instructions. However, some general steps are:

• Turn off and disconnect your dermoscopy from any power source or device.

• Wipe off any visible dirt or debris from the dermoscopy with a soft cloth or tissue.

• Disinfect the dermoscopy with an alcohol-based wipe or spray, or a disinfectant solution recommended by the manufacturer. Make sure to cover all surfaces, especially the lens and contact plate.

• Let the dermoscopy air dry completely before storing it in a clean and dry place.

• Do not use abrasive or corrosive cleaners, solvents, or detergents that may damage the dermoscopy.

• Do not immerse the dermoscopy in water or any liquid, unless it is waterproof and designed for immersion.

You should clean your dermoscopy after each use, or at least once a day if you use it frequently. You should also check your dermoscopy regularly for any signs of damage or malfunction, and contact the manufacturer or service provider if needed.

Polarized VS Non-polarized Dermoscopy

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can improve the diagnose accuracy of skin lesions, such as melanoma,basal cell carcinoma, seborrheic keratosis, etc.

There are two main types of dermoscopy: Non polarized and polarized dermoscopy.We’ve fitted most of our dermoscopys with polarized and non-polarized light. They canbe used in multiple skin structures.

Non-polarized contact Mode

In non-polarized mode, the instrument can provide information about the superficialskin structures, such as milia-like cysts, comedo-like openings, and pigment in theepidemis.

The dermoscopy requires applying a liquid such as mineral oil or alcohol to the skin andplacing the lens in contact with the skin. This reduces surface reflection and enhancesthe view of subsurface structures.

Image with non-polarized light (DE-3100)

Polarized contact Mode

In polarized mode, the instrument allows for visualization for deeper skin structures,such as blood vessels, collagen, and pigment in the dermis.

The dermoscopy does not need to be in contact with the skin or use any liquid. Theirpolarized light can help to eliminate surface reflection and allow visualization ofvascular structures.

Image with polarized light (DE-3100)

Polarized non-contact Mode

The dermoscopy can also use polarized light to examine the skin without direct contact.

In polarized non-contact mode, the instrument allows for examination infected areasand lesions that are painful for the patient, or the difficult to contact pigmented lesions,such as nails and narrow areas.

The contact plate should be removed in this mode, and it does not require applying aliquid to the skin. As it doesn’t require pressure or fluid application on the skin, it canalso avoid cross-contamination and infection risk.

Image in polarized non-contact mode (DE-3100)

How effectiveness is dermoscopy

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination. The dermoscopy allows the

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination.

The dermoscopy allows the examination of skin lesions with magnification and illumination. This can be greatly avoiding the factors that cause interference to visual detection. Such as lighting, skin color, hair and cosmetics.

Several studies have demonstrated that dermoscopy is useful in the identification of melanoma, when used by a trained professional.

It may improve the accuracy of clinical diagnosis by up to 35%
It may reduce the number of harmless lesions that are removed
In primary care, it may increase the referral of more worrisome lesions and reduce the referral of more trivial ones

A 2018 Cochrane meta-analysis published the accuracy of dermoscopy in the detection.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 76 75 3.04 0.32
Dermoscopy with visual inspection (in person) 92 95 18 0.08
Image-based visual inspection alone (not in person) 47 42 0.81 1.3
Dermoscopy with image-based visual inspection (not in person) 81 82 4.5 0.23
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

As we can see, the dermoscope can improve the accuracy of diagnosis of skin lesions, especially melanoma.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 79 77 3.4 0.27
Dermoscopy with visual inspection (in person) 93 99 93 0.07
Image-based visual inspection alone (not in person) 85 87 6.5 0.17
Dermoscopy with image-based visual inspection (not in person) 93 96 23 0.07
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

Characteristics of the dermatoscopic structure of the skin lesions include:

• Symmetry or asymmetry
• Homogeny/uniformity (sameness) or heterogeny (structural differences across the lesion)
• Distribution of pigment: brown lines, dots, clods and structureless areas
• Skin surface keratin: small white cysts, crypts, fissures
• Vascular morphology and pattern: regular or irregular
• Border of the lesion: fading, sharply cut off or radial streaks
• Presence of ulceration

There are specific dermoscopic patterns that aid in the diagnosis of the following pigmented skin lesions:

• Melanoma
• Moles (benign melanocytic naevus)
• Freckles (lentigos)
• Atypical naevi
• Blue naevi
• Seborrhoeic keratosis
• Pigmented basal cell carcinoma
• Haemangioma

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