What Are the Differences Between IBOOLO DE-300, DE-400, and DE-500? – IBOOLO

Shenzhen Iboolo Optics Co.Ltd was established in 2012,which is a a high-tech enterprise engaged in camera lens design, construction, product design, production, after-sale service, etc. For more than 11+ years, Shenzhen Iboolo Optics Co.Ltd has developed multiple advanced technologies in this field and became one of the leading contributor in the industry.

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What Are the Differences Between IBOOLO DE-300, DE-400, and DE-500?

A dermatoscope is a medical optical device designed to visualize skin structures that are not visible to the naked eye. By combining magnification with controlled illumination, a dermatoscope allows clearer observation of pigmentation, vascular patterns, and surface structures of the skin. Modern dermatoscopes increasingly rely on digital integration. Pocket dermatoscopes that connect to smartphones have…

A dermatoscope is a medical optical device designed to visualize skin structures that are not visible to the naked eye. By combining magnification with controlled illumination, a dermatoscope allows clearer observation of pigmentation, vascular patterns, and surface structures of the skin.

Modern dermatoscopes increasingly rely on digital integration. Pocket dermatoscopes that connect to smartphones have become popular because they are portable, easy to document, and suitable for telemedicine, education, and routine clinical use. The IBOOLO DE-300, DE-400, and DE-500 belong to this category and are designed for users who prefer compact devices with digital imaging capability.

What Do the IBOOLO DE-300, DE-400, and DE-500 Have in Common?

The most important shared feature of the DE-300, DE-400, and DE-500 is that all three are pocket dermatoscopes that must be connected to a smartphone for skin observation. Unlike handheld standalone dermatoscopes that allow direct visual inspection through an eyepiece, these models rely on a mobile device screen to display images. This design supports image capture, storage, and sharing, which are valuable for follow-up, consultation, and clinical documentation.

All three models support both polarized and non-polarized lighting modes. This dual-mode capability allows users to examine both superficial skin features, such as scales and surface texture, and deeper structures, such as pigment networks and blood vessels. In addition, all three devices are compact, lightweight, and designed for easy transport in clinical or field settings.

IBOOLO DE-300&DE-500&DE-400
IBOOLO DE-300&DE-500&DE-400

How Does Magnification Differ Between DE-300 and the Other Models?

One of the most fundamental differences among the three models is magnification. The IBOOLO DE-300 offers 6X magnification, while both the DE-400 and DE-500 provide 10X magnification. Magnification directly influences the level of detail that can be visualized. A 6X magnification is sufficient for general observation of many skin lesions and may be suitable for basic screening or educational use.

In contrast, 10X magnification allows for more detailed visualization of fine pigment structures and vascular patterns, which is particularly useful in dermatological evaluation. Users who require higher diagnostic precision or who frequently assess complex lesions may benefit from the increased magnification offered by the DE-400 and DE-500.

IBOOLO DE-300 Dermatoscope
IBOOLO DE-300 Dermatoscope

Why Do Optical Lens Quality and Image Performance Matter?

Beyond magnification, optical lens quality plays a crucial role in image clarity, distortion control, and overall diagnostic confidence. The three models differ significantly in this aspect. The DE-300 uses a standard lens system designed to meet basic clinical and educational needs. The DE-400 features an improved lens compared with the DE-300, offering clearer imaging and better detail resolution.

The DE-500 represents the highest optical level among the three. It is equipped with IBOOLO’s latest-generation lens, which provides superior image sharpness, reduced distortion, and improved color fidelity. These optical improvements enhance the visibility of subtle structures and minimize visual artifacts, which is especially important for detailed dermoscopic assessment and high-quality image documentation.

IBOOLO DE-400 Dermatoscope
IBOOLO DE-400 Dermatoscope

How Do Lighting Modes Differ Across the Three Models?

All three models support polarized and non-polarized lighting, which is a core requirement for dermoscopy. Polarized light reduces surface reflection and allows visualization of deeper skin structures, while non-polarized light highlights superficial features when used with direct skin contact.

The DE-500 includes an additional UV lighting mode. UV illumination is a vital tool for identifying bacterial or fungal infections and assessing pigmentation depth. By including UV functionality, the DE-500 expands its diagnostic utility far beyond that of the DE-300 and DE-400.

What Are the Differences in Battery Capacity and Power Design?

Battery capacity is another important practical difference. Both the DE-300 and DE-400 are equipped with a 200 mAh battery, which supports standard usage patterns for routine clinical or educational sessions. The DE-500 features a larger 300 mAh battery, providing extended operating time to accommodate its additional functions and higher performance requirements.

For users who require longer observation sessions or frequent switching between lighting modes, the increased battery capacity of the DE-500 offers greater convenience and reliability.

IBOOLO DE-500 Dermatoscope
IBOOLO DE-500 Dermatoscope

How Do Prices Reflect Functional Differences?

Pricing among the three models reflects their differences in magnification, optics, features, and design complexity. The IBOOLO DE-300 is priced at 109 USD, making it an accessible option for users who need basic dermoscopic functionality. The DE-400 is priced at 179 USD and offers higher magnification and improved image quality, positioning it as a mid-range choice.

The DE-500 is priced at 399 USD, reflecting its advanced optical system, UV capability, higher battery capacity, and updated design features. Its price aligns with its role as a high-performance device for users who require advanced functionality and image quality.

What Warranty and Support Are Provided?

All IBOOLO DE-300, DE-400, and DE-500 dermatoscopes come with a two-year warranty. During the warranty period, any product malfunction is covered by free repair or replacement services. And if you have any questions while using the product, feel free to contact us by email at iboolo@iboolo.com.

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How can dermoscopy images be captured?

Dermoscopy images can be captured and stored in different ways, such as: • Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.• Using a digital camera

Dermoscopy images can be captured and stored in different ways, such as:

• Using a smartphone or tablet with dermoscopic adapter, which consisted in the package.
• Using a digital camera with dermoscopic adapter, there’s 49mm screw size camera adapter available to order now.

Compatible phone/tablet models:
All iPhone models, 95% Android phones, 90% tablet. For phone/tablet size in 5.25-14mm

Compatible camera models:
All camera with built 49mm filter screw, such as Canon EOS 70D, 80D, 90D; Canon EOS R7, R10, R50, R100; Canon M100, M200, M50, Mark II; Canon G7X Mark III, Sony ZV-1

How can I connect my phone to my dermatoscope?

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide. Smartphone Connector (1) Place phone adapter screw in the center of smartphone’s

There’s universal phone adapter for all our dermoscopes. Please check the installation procedure bellow or watch operation guide.

Smartphone Connector

(1) Place phone adapter screw in the center of smartphone’s main camera.
(2) Screw magnet attachment on phone adapter.
(3) Put dermoscope’s back ring and magnet attachment together

Take The Best Images

You need to adjust the focus ring after the dermoscpe connected on smartphone to get the best images.

How can I clean my dermoscopy after usage?

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always

Cleaning your dermoscopy after usage is important to prevent cross-contamination and infection. The cleaning method may vary depending on the type and model of your dermoscopy, so you should always follow the manufacturer’s instructions. However, some general steps are:

• Turn off and disconnect your dermoscopy from any power source or device.

• Wipe off any visible dirt or debris from the dermoscopy with a soft cloth or tissue.

• Disinfect the dermoscopy with an alcohol-based wipe or spray, or a disinfectant solution recommended by the manufacturer. Make sure to cover all surfaces, especially the lens and contact plate.

• Let the dermoscopy air dry completely before storing it in a clean and dry place.

• Do not use abrasive or corrosive cleaners, solvents, or detergents that may damage the dermoscopy.

• Do not immerse the dermoscopy in water or any liquid, unless it is waterproof and designed for immersion.

You should clean your dermoscopy after each use, or at least once a day if you use it frequently. You should also check your dermoscopy regularly for any signs of damage or malfunction, and contact the manufacturer or service provider if needed.

Polarized VS Non-polarized Dermoscopy

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can

A dermoscopy is a device that allows the examination of skin lesions with magnificationand illumination. By revealing subsurface structures and patterns that are not visible tothe naked eye. It can improve the diagnose accuracy of skin lesions, such as melanoma,basal cell carcinoma, seborrheic keratosis, etc.

There are two main types of dermoscopy: Non polarized and polarized dermoscopy.We’ve fitted most of our dermoscopys with polarized and non-polarized light. They canbe used in multiple skin structures.

Non-polarized contact Mode

In non-polarized mode, the instrument can provide information about the superficialskin structures, such as milia-like cysts, comedo-like openings, and pigment in theepidemis.

The dermoscopy requires applying a liquid such as mineral oil or alcohol to the skin andplacing the lens in contact with the skin. This reduces surface reflection and enhancesthe view of subsurface structures.

Image with non-polarized light (DE-3100)

Polarized contact Mode

In polarized mode, the instrument allows for visualization for deeper skin structures,such as blood vessels, collagen, and pigment in the dermis.

The dermoscopy does not need to be in contact with the skin or use any liquid. Theirpolarized light can help to eliminate surface reflection and allow visualization ofvascular structures.

Image with polarized light (DE-3100)

Polarized non-contact Mode

The dermoscopy can also use polarized light to examine the skin without direct contact.

In polarized non-contact mode, the instrument allows for examination infected areasand lesions that are painful for the patient, or the difficult to contact pigmented lesions,such as nails and narrow areas.

The contact plate should be removed in this mode, and it does not require applying aliquid to the skin. As it doesn’t require pressure or fluid application on the skin, it canalso avoid cross-contamination and infection risk.

Image in polarized non-contact mode (DE-3100)

How effectiveness is dermoscopy

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination. The dermoscopy allows the

Compared with visual inspection, the dermoscopy can be used to capture and store skin lesion photos, which play an important role in early skin cancer examination.

The dermoscopy allows the examination of skin lesions with magnification and illumination. This can be greatly avoiding the factors that cause interference to visual detection. Such as lighting, skin color, hair and cosmetics.

Several studies have demonstrated that dermoscopy is useful in the identification of melanoma, when used by a trained professional.

It may improve the accuracy of clinical diagnosis by up to 35%
It may reduce the number of harmless lesions that are removed
In primary care, it may increase the referral of more worrisome lesions and reduce the referral of more trivial ones

A 2018 Cochrane meta-analysis published the accuracy of dermoscopy in the detection.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 76 75 3.04 0.32
Dermoscopy with visual inspection (in person) 92 95 18 0.08
Image-based visual inspection alone (not in person) 47 42 0.81 1.3
Dermoscopy with image-based visual inspection (not in person) 81 82 4.5 0.23
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

As we can see, the dermoscope can improve the accuracy of diagnosis of skin lesions, especially melanoma.

Table 1. Accuracy of dermoscopy in the detection of melanoma in adults
Detection Method Sensitivity, % Specificity, % Positive Likelihood Ratio NegativeLikelihood Ratio
Visual inspection alone (in person) 79 77 3.4 0.27
Dermoscopy with visual inspection (in person) 93 99 93 0.07
Image-based visual inspection alone (not in person) 85 87 6.5 0.17
Dermoscopy with image-based visual inspection (not in person) 93 96 23 0.07
ROC—receiver operating characteristic. *Estimated sensitivity calculated on the summary ROC curve at a fixed specificity of 80%.

Characteristics of the dermatoscopic structure of the skin lesions include:

• Symmetry or asymmetry
• Homogeny/uniformity (sameness) or heterogeny (structural differences across the lesion)
• Distribution of pigment: brown lines, dots, clods and structureless areas
• Skin surface keratin: small white cysts, crypts, fissures
• Vascular morphology and pattern: regular or irregular
• Border of the lesion: fading, sharply cut off or radial streaks
• Presence of ulceration

There are specific dermoscopic patterns that aid in the diagnosis of the following pigmented skin lesions:

• Melanoma
• Moles (benign melanocytic naevus)
• Freckles (lentigos)
• Atypical naevi
• Blue naevi
• Seborrhoeic keratosis
• Pigmented basal cell carcinoma
• Haemangioma

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